Download PDF by Sudarshan K. Malhotra: Advances in Neural Science, Volume 2 (Advances in Neural

By Sudarshan K. Malhotra

ISBN-10: 0080526403

ISBN-13: 9780080526409

ISBN-10: 1559386258

ISBN-13: 9781559386258

A part of a sequence which goals to hide fresh wisdom within the box of neural technological know-how, this quantity discusses such issues as: the molecular bases of nerve regeneration; plasticity of descending spinal pathways in constructing mammals; and improvement of the mammalian auditory hindbrain.

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Extra info for Advances in Neural Science, Volume 2 (Advances in Neural Science)

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The glial factors responsible for the SRIF secretion remain to be investigated. The influence of non-neuronal factors on SP and SRIF metabolism has been extensively studied in sympathetic and sensory neurons in culture (Kessler, 1984). They found that non-neuronal cells exert a profound influence on the sympathetic expression of these peptides. Sympathetic neurons cultured without associated non-neuronal cells contain virtually no SP but do express SRIE whereas neurons grown in the presence of ganglion non-neuronal cells contain substantial levels of both peptides.

It is known that not all AChE-containing neurons also contain CHAT, the cholinergic neuronal marker. , 1984). More recently, Van der Zee et al. (1991) have reported colocalization of muscarinic Ach receptors and SRIF in nonpyramidal neurons of the rat dorsal hippocampus. This finding provides additional evidence for a direct cholinergic influence upon somatostatinergic nonpyramidal neurons and defines the coexistence of SRIF and cholinoceptive neurons in the dorsal hippocampus. Forloni et al. (1989) also examined the distribution of AChE staining and SLI in mouse hippocampus during postnatal development.

In contrast, our data suggest that the effect of GHRH administered to chick embryos during a critical period of neuroembryogenesis, from E 1 to E3, may enhance the survival of catecholaminergic neurons in the brain, the increased viability being reflected as an increase in TH activity. The apparent discrepancy between our findings and those of Brenneman and Foster may reflect the difference between the in vivo and in vitro systems. The role of GHRH as a neuromodulator has only recently been investigated with the report of Rivier et al.

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Advances in Neural Science, Volume 2 (Advances in Neural Science) by Sudarshan K. Malhotra


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