By A. Armstrong
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Extra info for Advances in Malignant Melanoma - Clinical, Research Perspectives
2010). In this chapter, we review the link between melanoma and skin complexion, focusing on the genes that control innate and adaptive skin pigmentation and the mechanisms by which pigmentation differences may account for melanoma risk. 2. Melanoma - A growing problem According to the World Health Organization, about 132,000 people will be diagnosed with malignant melanoma of the skin each year. Mainly a disease of fair-skinned individuals, it is most prevalent in Western nations in which the majority of the population has descended from Northern European ancestry (Tucker, 2009; Rigel, 2010).
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Transplantation 61, 274278. , and Besaratinia, A. (2005). Mutations induced by ultraviolet light. Mutat Res 571, 19-31. , and Przybilla, B. (1997). Malignant melanoma and levodopa: is there a relationship? Two new cases and a review of the literature. J Am Acad Dermatol 37, 332-336. , and Duvic, M. (2003). Mycosis fungoides associated with malignant melanoma and dysplastic nevus syndrome. Int J Dermatol 42, 116-122. R. (2010). A comprehensive catalogue of somatic mutations from a human cancer genome.
Advances in Malignant Melanoma - Clinical, Research Perspectives by A. Armstrong